Caluire et Cuire is a commune in the Metropolis of Lyon in Auvergne-Rhône-Alpes region in eastern France.It is the fifth-largest suburb of the city of Lyon, and lies 4 km north-by-east of Lyon.Quarters Le Bourg Vassieux Cuire-le-Bas (quarter) Cuire-le-Haut (quarter) Saint-Clair Le Vernay Montessuy Bissardon