the AO premise:
the first and second vertebrae in the neck should line up with the skull (occiput) at right angles or orthogonally.
if they are not orthogonal, subsequent imbalance of body structure will eventuate due to compensatory changes.
compensatory changes are affected by nervous system interference, irritation or dysfunction.
this may lead to poor organ function, muscle spasm causing shoulder or pelvic girdle distortion, over time, if not corrected